Five and I is the colloquial name for the intersection of West Fifth Street and Ivy Street. The area is the commercial core of the South Campus Neighborhood. Businesses in the area include Riley's, Franky's, Cafe Paulo, the Fifth and Ivy Market, Five and Eye, and Tacos de Acapulco. There are several fraternities and sororities in the immediate vicinity also.

Historically, this was the site of the Chico Soda Works, and A.G. Eames' residence.