Rex Hospital is Raleigh's oldest hospital. If was founded by John T. Rex in 1894 and purchased in 1999 by UNC Health Care.

Rex has 1 emergency dept at the main hospital (see map), and several urgent care facilities(Rex Urgent Care of Cary, RUC Wakefield, RUC Holly Spring, RUC Wakefield).  RUC Holly Springs  will be converted into a full hospital soon.  Rex also has 3 networks of united physicians in the ambulatory setting - Triangle Physicians Network, Rex Physicians LLC, and Rex Healthcare.