John Francis Shelley (1905–1974) was an American politician and lawyer. He served as the 35th Mayor of San Francisco, California, from January 8, 1964 – January 8, 1968. He also served as a Member of the U.S. House of Representatives from California's 5th district, from November 8, 1949 – January 7, 1964.

Shelley's term as mayor was filled with challenges, including various strikes discriminatory hiring practices against African-Americans at the Palace Hotel, a public nurse strike in 1966, and a threatened San Francisco Symphony Orchestra strike in 1967. While mayor, the city experienced the Summer of Love, a time of radicalism in the Haight-Ashbury and turmoil throughout the city and six days of riots in Bayview-Hunters Point starting on September 27, 1966 (after a white police officer fatally shot a Black youth accused of auto theft).

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